Take Exit 45A For Downtown East-West, Merge Onto I-275 N, Keep Right To Stay On I-275 N, Follow Signs For Interstate 4 E/Orlando, Take Exit 45B For I-4 E Toward Orlando, Merge Onto I-4 E, Take Exit 1 For 21St St/22Nd St Toward Port Of Tampa, Keep Right At The Fork, Follow Signs For Downtown-East, Merge Onto E 14Th Ave, Turn Right Onto N 21St St, Turn Left At The 3Rd Cross Street Onto E Columbus Dr, Turn Right Onto N Jefferson St, Turn Left At The First Cross Street Onto W Adalee St, And You'll Find 109 W Adalee St On Your Left.